Gene description for Aats-glupro
Gene name Glutamyl-prolyl-tRNA synthetase
Gene symbol Aats-glupro
Other names/aliases AATS
AATs-GluPro
Aa-tRNA-syn-glupro
Aats-glu
CG5394
DmelCG5394
EPRS
ERS
GluPro-RS
GluProRS
GluRS
aminoacyl-tRNA synthetase
glutamyl-prolyl-tRNA synthetase
p200
Species Drosophila melanogaster
 Database cross references - Aats-glupro
ExoCarta ExoCarta_42834
Entrez Gene 42834
UniProt P28668  
 Aats-glupro identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Aats-glupro
Molecular Function
    ATP binding GO:0005524 IEA
    glutamate-tRNA ligase activity GO:0004818 NAS
    proline-tRNA ligase activity GO:0004827 NAS
Biological Process
    prolyl-tRNA aminoacylation GO:0006433 ISS
    glutamyl-tRNA aminoacylation GO:0006424 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    aminoacyl-tRNA synthetase multienzyme complex GO:0017101 NAS
 Experiment description of studies that identified Aats-glupro in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aats-glupro
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aats-glupro is involved
No pathways found





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