Gene description for Aats-glupro
Gene name Glutamyl-prolyl-tRNA synthetase
Gene symbol Aats-glupro
Other names/aliases AATS
AATs-GluPro
Aa-tRNA-syn-glupro
Aats-glu
CG5394
DmelCG5394
EPRS
ERS
GluPro-RS
GluProRS
GluRS
aminoacyl-tRNA synthetase
glutamyl-prolyl-tRNA synthetase
p200
Species Drosophila melanogaster
 Database cross references - Aats-glupro
ExoCarta ExoCarta_42834
Vesiclepedia VP_42834
Entrez Gene 42834
UniProt P28668  
 Aats-glupro identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Aats-glupro
Molecular Function
    glutamate-tRNA ligase activity GO:0004818 IDA
    glutamate-tRNA ligase activity GO:0004818 TAS
    proline-tRNA ligase activity GO:0004827 IDA
    proline-tRNA ligase activity GO:0004827 TAS
Biological Process
    glutamyl-tRNA aminoacylation GO:0006424 IDA
    glutamyl-tRNA aminoacylation GO:0006424 TAS
    prolyl-tRNA aminoacylation GO:0006433 IDA
    prolyl-tRNA aminoacylation GO:0006433 TAS
Subcellular Localization
    cytoplasm GO:0005737 TAS
    aminoacyl-tRNA synthetase multienzyme complex GO:0017101 IDA
 Experiment description of studies that identified Aats-glupro in exosomes
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aats-glupro
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG5525  
Affinity Capture-MS Drosophila melanogaster
2 Cyp12d1-p  
Affinity Capture-MS Drosophila melanogaster
3 CG12304  
Affinity Capture-MS Drosophila melanogaster
4 CG4729  
Affinity Capture-MS Drosophila melanogaster
5 Sec61alpha  
Affinity Capture-MS Drosophila melanogaster
6 Tcp-1zeta 32518
Affinity Capture-MS Drosophila melanogaster
7 Aats-gln  
Affinity Capture-MS Drosophila melanogaster
8 CG8235  
Affinity Capture-MS Drosophila melanogaster
9 CG8258 35882
Affinity Capture-MS Drosophila melanogaster
10 r  
Affinity Capture-MS Drosophila melanogaster
11 CG15100  
Affinity Capture-MS Drosophila melanogaster
12 Mpcp  
Affinity Capture-MS Drosophila melanogaster
13 CG15211  
Two-hybrid Drosophila melanogaster
14 CG17259  
Affinity Capture-MS Drosophila melanogaster
15 Gp93  
Affinity Capture-MS Drosophila melanogaster
16 CG2064  
Affinity Capture-MS Drosophila melanogaster
17 TER94  
Two-hybrid Drosophila melanogaster
Affinity Capture-MS Drosophila melanogaster
18 Chc 32537
Affinity Capture-MS Drosophila melanogaster
19 cry  
Proximity Label-MS Drosophila melanogaster
20 CG8331  
Two-hybrid Drosophila melanogaster
21 Pp2A-29B  
Affinity Capture-MS Drosophila melanogaster
22 Gsc  
Two-hybrid Drosophila melanogaster
23 Pi3K68D  
Affinity Capture-MS Drosophila melanogaster
24 Aats-asp  
Affinity Capture-MS Drosophila melanogaster
25 CG33303  
Affinity Capture-MS Drosophila melanogaster
26 CG14894  
Proximity Label-MS Drosophila melanogaster
27 RpS5a  
Affinity Capture-MS Drosophila melanogaster
28 MRP  
Affinity Capture-MS Drosophila melanogaster
29 Rpn1 40174
Affinity Capture-MS Drosophila melanogaster
30 CG12262  
Affinity Capture-MS Drosophila melanogaster
31 Kap-alpha3  
Affinity Capture-MS Drosophila melanogaster
32 Kr-h2  
Affinity Capture-MS Drosophila melanogaster
33 Cctgamma 42029
Affinity Capture-MS Drosophila melanogaster
34 msk 44747
Affinity Capture-MS Drosophila melanogaster
35 Ranbp9  
Affinity Capture-MS Drosophila melanogaster
36 Gfat2  
Affinity Capture-MS Drosophila melanogaster
37 OstDelta  
Affinity Capture-MS Drosophila melanogaster
38 Vps4  
Affinity Capture-MS Drosophila melanogaster
39 CG1516  
Affinity Capture-MS Drosophila melanogaster
40 Aats-ile 45785
Affinity Capture-MS Drosophila melanogaster
41 bor  
Affinity Capture-MS Drosophila melanogaster
42 Aats-arg  
Affinity Capture-MS Drosophila melanogaster
43 Pex13  
Two-hybrid Drosophila melanogaster
44 betaCOP  
Affinity Capture-MS Drosophila melanogaster
45 l(1)G0156  
Affinity Capture-MS Drosophila melanogaster
46 CG12264  
Affinity Capture-MS Drosophila melanogaster
47 Cnx99A  
Affinity Capture-MS Drosophila melanogaster
48 Sucb  
Affinity Capture-MS Drosophila melanogaster
49 Sec63  
Affinity Capture-MS Drosophila melanogaster
50 CG1371  
Affinity Capture-MS Drosophila melanogaster
51 Rtnl1  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here