Gene description for CG8258
Gene name CG8258 gene product from transcript CG8258-RA
Gene symbol CG8258
Other names/aliases CCT8
DmelCG8258
Q7K3J0_DROME
TCP-1theta
Tcp1-theta
Species Drosophila melanogaster
 Database cross references - CG8258
ExoCarta ExoCarta_35882
Vesiclepedia VP_35882
Entrez Gene 35882
 CG8258 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG8258
Subcellular Localization
    plasma membrane GO:0005886 HDA
 Experiment description of studies that identified CG8258 in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG8258
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG5525  
Affinity Capture-MS Drosophila melanogaster
2 CG7033  
Affinity Capture-MS Drosophila melanogaster
3 Cyp12d1-p  
Affinity Capture-MS Drosophila melanogaster
4 CG14482  
Affinity Capture-MS Drosophila melanogaster
5 shd  
Affinity Capture-MS Drosophila melanogaster
6 Tcp-1zeta 32518
Affinity Capture-MS Drosophila melanogaster
7 boca  
Affinity Capture-MS Drosophila melanogaster
8 CG4169  
Affinity Capture-MS Drosophila melanogaster
9 Rpt6  
Affinity Capture-MS Drosophila melanogaster
10 TER94  
Affinity Capture-MS Drosophila melanogaster
11 bor  
Affinity Capture-MS Drosophila melanogaster
12 Mpcp  
Affinity Capture-MS Drosophila melanogaster
13 CG3523 33524
Affinity Capture-MS Drosophila melanogaster
14 Past1  
Affinity Capture-MS Drosophila melanogaster
15 PDCL 5082
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
16 CG17259  
Affinity Capture-MS Drosophila melanogaster
17 CG2064  
Affinity Capture-MS Drosophila melanogaster
18 Tcp-1eta 41054
Affinity Capture-MS Drosophila melanogaster
19 Rpt1  
Affinity Capture-MS Drosophila melanogaster
20 Gfat2  
Affinity Capture-MS Drosophila melanogaster
21 imd  
Affinity Capture-MS Drosophila melanogaster
22 Ost48  
Affinity Capture-MS Drosophila melanogaster
23 Sucb  
Affinity Capture-MS Drosophila melanogaster
24 CG1444  
Affinity Capture-MS Drosophila melanogaster
25 Sec61alpha  
Affinity Capture-MS Drosophila melanogaster
26 Pp2A-29B  
Affinity Capture-MS Drosophila melanogaster
27 Pi3K68D  
Affinity Capture-MS Drosophila melanogaster
28 Gp93  
Affinity Capture-MS Drosophila melanogaster
29 T-cp1 42649
Affinity Capture-MS Drosophila melanogaster
30 CG33303  
Affinity Capture-MS Drosophila melanogaster
31 viaf  
Affinity Capture-MS Drosophila melanogaster
32 wal  
Affinity Capture-MS Drosophila melanogaster
33 Iap2  
Affinity Capture-MS Drosophila melanogaster
34 Gp210  
Affinity Capture-MS Drosophila melanogaster
35 MRP  
Affinity Capture-MS Drosophila melanogaster
36 CG17337  
Affinity Capture-MS Drosophila melanogaster
37 CG1371  
Affinity Capture-MS Drosophila melanogaster
38 Hira  
Affinity Capture-MS Drosophila melanogaster
39 yellow-g  
Two-hybrid Drosophila melanogaster
40 Tak1  
Affinity Capture-MS Drosophila melanogaster
41 Cct5  
Affinity Capture-MS Drosophila melanogaster
42 Glt  
Affinity Capture-MS Drosophila melanogaster
43 Rpn1 40174
Affinity Capture-MS Drosophila melanogaster
44 CG12262  
Affinity Capture-MS Drosophila melanogaster
45 Psa  
Affinity Capture-MS Drosophila melanogaster
46 Kap-alpha3  
Affinity Capture-MS Drosophila melanogaster
47 Mec2 32905
Affinity Capture-MS Drosophila melanogaster
48 Cctgamma 42029
Affinity Capture-MS Drosophila melanogaster
49 skap  
Affinity Capture-MS Drosophila melanogaster
50 Dredd  
Affinity Capture-MS Drosophila melanogaster
51 Ranbp9  
Affinity Capture-MS Drosophila melanogaster
52 Rel  
Affinity Capture-MS Drosophila melanogaster
53 Kr-h2  
Affinity Capture-MS Drosophila melanogaster
54 GNB1 2782
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
55 ird5  
Affinity Capture-MS Drosophila melanogaster
56 OstDelta  
Affinity Capture-MS Drosophila melanogaster
57 PGRP-LE  
Affinity Capture-MS Drosophila melanogaster
58 egl  
Proximity Label-MS Drosophila melanogaster
59 Rab7  
Affinity Capture-MS Drosophila melanogaster
60 Aats-glupro 42834
Affinity Capture-MS Drosophila melanogaster
61 fax  
Affinity Capture-MS Drosophila melanogaster
62 CG3313  
Affinity Capture-MS Drosophila melanogaster
63 Tab2  
Affinity Capture-MS Drosophila melanogaster
64 key  
Affinity Capture-MS Drosophila melanogaster
65 betaCOP  
Affinity Capture-MS Drosophila melanogaster
66 l(1)G0156  
Affinity Capture-MS Drosophila melanogaster
67 CG12264  
Affinity Capture-MS Drosophila melanogaster
68 Cnx99A  
Affinity Capture-MS Drosophila melanogaster
69 Fadd  
Affinity Capture-MS Drosophila melanogaster
70 CG3008  
Affinity Capture-MS Drosophila melanogaster
71 Vps4  
Affinity Capture-MS Drosophila melanogaster
72 Chc 32537
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which CG8258 is involved
No pathways found





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