Gene description for CG8258
Gene name CG8258 gene product from transcript CG8258-RA
Gene symbol CG8258
Other names/aliases CCT8
DmelCG8258
Q7K3J0_DROME
TCP-1theta
Tcp1-theta
Species Drosophila melanogaster
 Database cross references - CG8258
ExoCarta ExoCarta_35882
Entrez Gene 35882
 CG8258 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG8258
Molecular Function
    unfolded protein binding GO:0051082 IEA
    ATP binding GO:0005524 IEA
    ATPase activity, coupled GO:0042623 ISS
Biological Process
    cytoplasmic microtubule organization GO:0031122 IMP
    mitotic spindle organization GO:0007052 IMP
    protein folding GO:0006457 ISS
Subcellular Localization
    chaperonin-containing T-complex GO:0005832 ISS
    microtubule associated complex GO:0005875 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified CG8258 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG8258
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CG8258 is involved
No pathways found





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