Gene description for Mec2
Gene name CG7635 gene product from transcript CG7635-RA
Gene symbol Mec2
Other names/aliases CG7635
DMec2
DmelCG7635
Species Drosophila melanogaster
 Database cross references - Mec2
ExoCarta ExoCarta_32905
Entrez Gene 32905
 Mec2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Mec2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    nephrocyte filtration GO:0097206 IMP
Subcellular Localization
    membrane GO:0016020 IEA
    nephrocyte diaphragm GO:0005917 IC
 Experiment description of studies that identified Mec2 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mec2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mec2 is involved
No pathways found





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