Gene description for Tcp-1zeta
Gene name T-cp1zeta
Gene symbol Tcp-1zeta
Other names/aliases CCT6
CG8231
DmelCG8231
L(1)g0022
Q9VXQ5_DROME
Rcd3
TCP-1-zeta
TCP-1zeta
Tcp-1-zeta
l(1)G0022
l(1)G0027
l(1)G0057
Species Drosophila melanogaster
 Database cross references - Tcp-1zeta
ExoCarta ExoCarta_32518
Entrez Gene 32518
 Tcp-1zeta identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Tcp-1zeta
Molecular Function
    ATP binding GO:0005524 IEA
    unfolded protein binding GO:0051082 ISS
    ATPase activity, coupled GO:0042623 ISS
Biological Process
    cytoplasmic microtubule organization GO:0031122 IMP
    mitotic nuclear division GO:0007067 IMP
    mitotic spindle organization GO:0007052 IMP
    mitotic spindle assembly GO:0090307 IMP
    centriole replication GO:0007099 IMP
    protein folding GO:0006457 ISS
Subcellular Localization
    microtubule associated complex GO:0005875 IDA
    lipid particle GO:0005811 IDA
    chaperonin-containing T-complex GO:0005832 ISS
 Experiment description of studies that identified Tcp-1zeta in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tcp-1zeta
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tcp-1zeta is involved
No pathways found





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