Gene description for T-cp1
Gene name Tcp1-like
Gene symbol T-cp1
Other names/aliases BEST:GH05123
CCT1
CG5374
DmelCG5374
T-CP1
T-cpl
TCP-1alpha
TCP1alpha
TCPA_DROME
Tcp-1
Tcp1
Tcp1-alpha
gh05123
Species Drosophila melanogaster
 Database cross references - T-cp1
ExoCarta ExoCarta_42649
Vesiclepedia VP_42649
Entrez Gene 42649
UniProt P12613  
 T-cp1 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for T-cp1
Biological Process
    follicle cell of egg chamber development GO:0030707 IMP
Subcellular Localization
    cytosol GO:0005829 HDA
 Experiment description of studies that identified T-cp1 in sEVs
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for T-cp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG5525  
Affinity Capture-MS Drosophila melanogaster
2 CG7033  
Affinity Capture-MS Drosophila melanogaster
3 Tcp-1zeta 32518
Affinity Capture-MS Drosophila melanogaster
4 CG4169  
Affinity Capture-MS Drosophila melanogaster
5 CG8258 35882
Affinity Capture-MS Drosophila melanogaster
6 CG33303  
Affinity Capture-MS Drosophila melanogaster
7 CG3918  
Two-hybrid Drosophila melanogaster
8 PDCL 5082
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
9 Tcp-1eta 41054
Affinity Capture-MS Drosophila melanogaster
10 Rpt1  
Affinity Capture-MS Drosophila melanogaster
11 CG31731  
Two-hybrid Drosophila melanogaster
12 PyK  
Affinity Capture-MS Drosophila melanogaster
13 OS9  
Two-hybrid Drosophila melanogaster
14 wal  
Affinity Capture-MS Drosophila melanogaster
15 Iap2  
Affinity Capture-MS Drosophila melanogaster
16 GNB1 2782
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
17 Hira  
Affinity Capture-MS Drosophila melanogaster
18 Cct5  
Affinity Capture-MS Drosophila melanogaster
19 me31B  
Proximity Label-MS Drosophila melanogaster
20 Cctgamma 42029
Affinity Capture-MS Drosophila melanogaster
21 Cpr64Aa  
Two-hybrid Drosophila melanogaster
22 ird5  
Affinity Capture-MS Drosophila melanogaster
23 CTPsyn  
Proximity Label-MS Drosophila melanogaster
24 PGRP-LE  
Affinity Capture-MS Drosophila melanogaster
25 Tab2  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml



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