Gene description for cathD
Gene name CG1548 gene product from transcript CG1548-RA
Gene symbol cathD
Other names/aliases CATH
CG1548
CT3996
CTSD
CathD
DmelCG1548
T17
Species Drosophila melanogaster
 Database cross references - cathD
ExoCarta ExoCarta_45268
Vesiclepedia VP_45268
Entrez Gene 45268
 cathD identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for cathD
Biological Process
    apoptotic process GO:0006915 IMP
    nurse cell apoptotic process GO:0045476 IMP
    defense response to Gram-negative bacterium GO:0050829 IMP
Subcellular Localization
    extracellular region GO:0005576 HDA
    lysosome GO:0005764 IDA
 Experiment description of studies that identified cathD in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for cathD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Droj2  
Affinity Capture-MS Drosophila melanogaster
2 Cyp12d1-p  
Affinity Capture-MS Drosophila melanogaster
3 ImpL3 45880
Affinity Capture-MS Drosophila melanogaster
4 Rab5 33418
Affinity Capture-MS Drosophila melanogaster
5 Tcp-1zeta 32518
Affinity Capture-MS Drosophila melanogaster
6 CG4169  
Affinity Capture-MS Drosophila melanogaster
7 CG33303  
Affinity Capture-MS Drosophila melanogaster
8 skap  
Affinity Capture-MS Drosophila melanogaster
9 Sucb  
Affinity Capture-MS Drosophila melanogaster
10 CG5854 42831
Affinity Capture-MS Drosophila melanogaster
11 Tapdelta  
Affinity Capture-MS Drosophila melanogaster
12 CG14894  
Proximity Label-MS Drosophila melanogaster
13 Nf-YC  
Two-hybrid Drosophila melanogaster
14 Hel25E  
Affinity Capture-MS Drosophila melanogaster
15 Gp93  
Affinity Capture-MS Drosophila melanogaster
16 eIF4G2  
Two-hybrid Drosophila melanogaster
17 CG12262  
Affinity Capture-MS Drosophila melanogaster
18 SmB  
Two-hybrid Drosophila melanogaster
19 Mec2 32905
Affinity Capture-MS Drosophila melanogaster
20 me31B  
Proximity Label-MS Drosophila melanogaster
21 atl  
Affinity Capture-MS Drosophila melanogaster
22 Cctgamma 42029
Affinity Capture-MS Drosophila melanogaster
23 Vps25  
Two-hybrid Drosophila melanogaster
24 Ca-P60A  
Affinity Capture-MS Drosophila melanogaster
25 wal  
Affinity Capture-MS Drosophila melanogaster
26 Gfat2  
Affinity Capture-MS Drosophila melanogaster
27 MED4  
Affinity Capture-MS Drosophila melanogaster
28 CG12264  
Affinity Capture-MS Drosophila melanogaster
29 Cnx99A  
Affinity Capture-MS Drosophila melanogaster
30 Cp1  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which cathD is involved
No pathways found





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