Gene description for cathD
Gene name CG1548 gene product from transcript CG1548-RA
Gene symbol cathD
Other names/aliases CATH
CG1548
CT3996
CTSD
CathD
DmelCG1548
T17
Species Drosophila melanogaster
 Database cross references - cathD
ExoCarta ExoCarta_45268
Entrez Gene 45268
 cathD identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for cathD
Molecular Function
    aspartic-type endopeptidase activity GO:0004190 NAS
Biological Process
    proteolysis GO:0006508 IEA
    defense response to Gram-negative bacterium GO:0050829 IMP
    salivary gland cell autophagic cell death GO:0035071 IEP
    autophagic cell death GO:0048102 IEP
    nurse cell apoptotic process GO:0045476 IMP
    apoptotic process GO:0006915 IMP
Subcellular Localization
    microtubule associated complex GO:0005875 IDA
    extracellular region GO:0005576 IDA
    lysosome GO:0005764 IDA
 Experiment description of studies that identified cathD in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for cathD
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which cathD is involved
No pathways found





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