Gene description for Gale
Gene name UDP-galactose 4'-epimerase
Gene symbol Gale
Other names/aliases CG12030
DmelCG12030
GALE
dGALE
Species Drosophila melanogaster
 Database cross references - Gale
ExoCarta ExoCarta_38076
Entrez Gene 38076
UniProt Q9W0P5  
 Gale identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Gale
Molecular Function
    UDP-N-acetylglucosamine 4-epimerase activity GO:0003974 IMP
    coenzyme binding GO:0050662 IEA
    UDP-glucose 4-epimerase activity GO:0003978 NAS
Biological Process
    galactose metabolic process GO:0006012 NAS
    larval lymph gland hemopoiesis GO:0035167 IMP
 Experiment description of studies that identified Gale in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gale
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gale is involved
PathwayEvidenceSource
Galactose catabolism IEA Reactome





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