Gene description for GPR143
Gene name	G protein-coupled receptor 143
Gene symbol	GPR143
Other names/aliases	NYS6 OA1
Species	Homo sapiens
Database cross references - GPR143
ExoCarta	ExoCarta_4935
Vesiclepedia	VP_4935
Entrez Gene	4935
HGNC	20145
MIM	300808
UniProt	P51810
GPR143 identified in sEVs derived from the following tissue/cell type
Melanoma cells	25950383
Melanoma cells	25950383
Melanoma cells	25950383
Melanoma cells	25950383

Gene ontology annotations for GPR143

Molecular Function     G protein-coupled receptor activity GO:0004930 IDA     protein binding GO:0005515 IPI     dopamine binding GO:0035240 IBA     dopamine binding GO:0035240 IDA     L-DOPA receptor activity GO:0035643 IBA     L-DOPA receptor activity GO:0035643 IDA     L-DOPA binding GO:0072544 IBA     L-DOPA binding GO:0072544 IDA     L-tyrosine binding GO:0072545 IBA     L-tyrosine binding GO:0072545 IDA Biological Process     eye pigment biosynthetic process GO:0006726 TAS     signal transduction GO:0007165 TAS     G protein-coupled receptor signaling pathway GO:0007186 IBA     G protein-coupled receptor signaling pathway GO:0007186 IMP     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IDA     neuropeptide signaling pathway GO:0007218 IEA     visual perception GO:0007601 TAS     melanosome localization GO:0032400 IDA     melanosome transport GO:0032402 IDA     melanosome organization GO:0032438 IBA     melanosome organization GO:0032438 IMP     regulation of melanosome transport GO:1902908 IEA     regulation of melanosome organization GO:1903056 IEA Subcellular Localization     cytoplasm GO:0005737 TAS     lysosomal membrane GO:0005765 IDA     Golgi apparatus GO:0005794 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     membrane GO:0016020 TAS     apical plasma membrane GO:0016324 IDA     melanosome membrane GO:0033162 IBA     melanosome membrane GO:0033162 IDA     melanosome GO:0042470 IDA