Gene description for PLCL1
Gene name phospholipase C-like 1
Gene symbol PLCL1
Other names/aliases PLCE
PLCL
PLDL1
PPP1R127
PRIP
Species Homo sapiens
 Database cross references - PLCL1
ExoCarta ExoCarta_5334
Entrez Gene 5334
HGNC 9063
MIM 600597
UniProt Q15111  
 PLCL1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PLCL1
Molecular Function
    GABA receptor binding GO:0050811 IEA
    inositol 1,4,5 trisphosphate binding GO:0070679 IEA
    signal transducer activity GO:0004871 IEA
    phospholipase C activity GO:0004629 TAS
    phosphatidylinositol phospholipase C activity GO:0004435 IEA
Biological Process
    gamma-aminobutyric acid signaling pathway GO:0007214 IEA
    regulation of peptidyl-serine phosphorylation GO:0033135 IEA
    intracellular signal transduction GO:0035556 IEA
    positive regulation of receptor binding GO:1900122 IEA
    regulation of synaptic transmission, GABAergic GO:0032228 IEA
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PLCL1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PLCL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLCL1 is involved
No pathways found





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