Gene description for CLIC6
Gene name
chloride intracellular channel 6
Gene symbol
CLIC6
Other names/aliases
CLIC1L
Species
Homo sapiens
Database cross references - CLIC6
ExoCarta
ExoCarta_54102
Vesiclepedia
VP_54102
Entrez Gene
54102
HGNC
2065
MIM
615321
UniProt
Q96NY7
CLIC6 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells
Unpublished / Not applicable
Urine
19056867
Gene ontology annotations for CLIC6
Experiment description of studies that identified CLIC6 in sEVs
1
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
2
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for CLIC6
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DRD4
Two-hybrid
Homo sapiens
2
CLIC4
25932
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
CLIC5
53405
Affinity Capture-MS
Homo sapiens
4
DRD2
Two-hybrid
Homo sapiens
5
DRD3
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which CLIC6 is involved
No pathways found