Gene description for SH3TC1
Gene name
SH3 domain and tetratricopeptide repeats 1
Gene symbol
SH3TC1
Other names/aliases
-
Species
Homo sapiens
Database cross references - SH3TC1
ExoCarta
ExoCarta_54436
Vesiclepedia
VP_54436
Entrez Gene
54436
HGNC
26009
UniProt
Q8TE82
SH3TC1 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocytes
26054723
Gene ontology annotations for SH3TC1
Experiment description of studies that identified SH3TC1 in sEVs
1
Experiment ID
234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
Protein-protein interactions for SH3TC1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ILDR2
Affinity Capture-MS
Homo sapiens
2
SMARCA2
6595
Affinity Capture-MS
Homo sapiens
3
ATF6
Affinity Capture-MS
Homo sapiens
4
HNRNPH1
3187
Affinity Capture-RNA
Homo sapiens
View the network
image/svg+xml
Pathways in which SH3TC1 is involved
No pathways found