Gene description for Paf1
Gene name	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
Gene symbol	Paf1
Other names/aliases	5730511K23Rik AA675045
Species	Mus musculus
Database cross references - Paf1
ExoCarta	ExoCarta_54624
Vesiclepedia	VP_54624
Entrez Gene	54624
UniProt	Q8K2T8
Paf1 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Paf1

Molecular Function     RNA polymerase II complex binding GO:0000993 IBA     RNA polymerase II complex binding GO:0000993 ISO     RNA polymerase II complex binding GO:0000993 ISS     chromatin binding GO:0003682 IBA     chromatin binding GO:0003682 IDA     protein binding GO:0005515 IPI     protein binding GO:0005515 IPI Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     endodermal cell fate commitment GO:0001711 IMP     transcription elongation by RNA polymerase II GO:0006368 ISS     Wnt signaling pathway GO:0016055 IEA     stem cell population maintenance GO:0019827 IMP     mRNA 3'-end processing GO:0031124 ISO     mRNA 3'-end processing GO:0031124 ISS     protein localization to nucleus GO:0034504 IEA     protein localization to nucleus GO:0034504 ISO     negative regulation of myeloid cell differentiation GO:0045638 ISO     negative regulation of myeloid cell differentiation GO:0045638 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     cellular response to lipopolysaccharide GO:0071222 IDA     positive regulation of cell cycle G1/S phase transition GO:1902808 ISO     positive regulation of cell cycle G1/S phase transition GO:1902808 ISS Subcellular Localization     fibrillar center GO:0001650 IEA     fibrillar center GO:0001650 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     membrane GO:0016020 IEA     membrane GO:0016020 ISO     Cdc73/Paf1 complex GO:0016593 IBA     Cdc73/Paf1 complex GO:0016593 IPI     Cdc73/Paf1 complex GO:0016593 ISO     Cdc73/Paf1 complex GO:0016593 ISS     intracellular membrane-bounded organelle GO:0043231 ISO