Gene description for SLC29A3
Gene name solute carrier family 29 (equilibrative nucleoside transporter), member 3
Gene symbol SLC29A3
Other names/aliases ENT3
HCLAP
HJCD
PHID
Species Homo sapiens
 Database cross references - SLC29A3
ExoCarta ExoCarta_55315
Vesiclepedia VP_55315
Entrez Gene 55315
HGNC 23096
MIM 612373
UniProt Q9BZD2  
 SLC29A3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC29A3
Molecular Function
    neurotransmitter transmembrane transporter activity GO:0005326 IDA
    nucleoside transmembrane transporter activity GO:0005337 IBA
    nucleoside transmembrane transporter activity GO:0005337 IDA
    nucleoside transmembrane transporter activity GO:0005337 IMP
    nucleoside transmembrane transporter activity GO:0005337 TAS
    protein binding GO:0005515 IPI
    monoamine transmembrane transporter activity GO:0008504 IDA
    organic cation transmembrane transporter activity GO:0015101 IDA
    nucleobase transmembrane transporter activity GO:0015205 IDA
    guanine transmembrane transporter activity GO:0015208 IDA
    uracil transmembrane transporter activity GO:0015210 IDA
    cytidine transmembrane transporter activity GO:0015212 IDA
    uridine transmembrane transporter activity GO:0015213 IDA
Biological Process
    xenobiotic metabolic process GO:0006805 TAS
    neurotransmitter transport GO:0006836 IEA
    serotonin transport GO:0006837 IDA
    nucleobase transport GO:0015851 IDA
    nucleoside transport GO:0015858 IDA
    nucleoside transport GO:0015858 IMP
    cytidine transport GO:0015861 IDA
    uridine transmembrane transport GO:0015862 IDA
    dopamine transport GO:0015872 IDA
    norepinephrine transport GO:0015874 IDA
    adenosine transport GO:0032238 IDA
    adenosine transport GO:0032238 IMP
    inosine transport GO:0035340 IDA
    nucleoside transmembrane transport GO:1901642 IDA
    nucleoside transmembrane transport GO:1901642 IMP
    guanine transmembrane transport GO:1903716 IDA
    uracil transmembrane transport GO:1903791 IDA
    pyrimidine nucleobase transmembrane transport GO:1904082 IDA
    purine nucleobase transmembrane transport GO:1904823 IDA
Subcellular Localization
    mitochondrial outer membrane GO:0005741 TAS
    lysosomal membrane GO:0005765 HDA
    lysosomal membrane GO:0005765 IDA
    lysosomal membrane GO:0005765 TAS
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IBA
    late endosome membrane GO:0031902 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified SLC29A3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC29A3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CREB3  
Two-hybrid Homo sapiens
2 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml



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