Gene description for Eif3d
Gene name eukaryotic translation initiation factor 3, subunit D
Gene symbol Eif3d
Other names/aliases 66/67kDa
AA407891
Eif3s7
eIF3p66
Species Mus musculus
 Database cross references - Eif3d
ExoCarta ExoCarta_55944
Entrez Gene 55944
UniProt O70194  
 Eif3d identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Eif3d
Molecular Function
    translation initiation factor activity GO:0003743 ISO
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    formation of cytoplasmic translation initiation complex GO:0001732 IDA
    translational initiation GO:0006413 ISO
    translation GO:0006412 IEA
Subcellular Localization
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 IEA
    eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541 IDA
 Experiment description of studies that identified Eif3d in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Eif3d
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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