Gene description for Pitpnb
Gene name phosphatidylinositol transfer protein, beta
Gene symbol Pitpnb
Other names/aliases PI-TP-beta
Species Mus musculus
 Database cross references - Pitpnb
ExoCarta ExoCarta_56305
Vesiclepedia VP_56305
Entrez Gene 56305
UniProt P53811  
 Pitpnb identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Pitpnb
Molecular Function
    phospholipid binding GO:0005543 ISA
    lipid binding GO:0008289 IEA
    phosphatidylinositol transporter activity GO:0008526 ISO
Biological Process
    phospholipid transport GO:0015914 ISO
    in utero embryonic development GO:0001701 IMP
    transport GO:0006810 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    intracellular GO:0005622 IEA
    extracellular exosome GO:0070062 ISO
    Golgi apparatus GO:0005794 IEA
 Experiment description of studies that identified Pitpnb in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Pitpnb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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