Gene description for Adar
Gene name	adenosine deaminase, RNA-specific
Gene symbol	Adar
Other names/aliases	AV242451 Adar1 Adar1p110 Adar1p150 mZaADAR
Species	Mus musculus
Database cross references - Adar
ExoCarta	ExoCarta_56417
Vesiclepedia	VP_56417
Entrez Gene	56417
UniProt	Q99MU3
Adar identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Adar

Molecular Function     left-handed Z-DNA binding GO:0003692 TAS     RNA binding GO:0003723 IEA     double-stranded RNA binding GO:0003725 IBA     double-stranded RNA adenosine deaminase activity GO:0003726 IBA     double-stranded RNA adenosine deaminase activity GO:0003726 ISO     adenosine deaminase activity GO:0004000 IEA     protein binding GO:0005515 IPI     tRNA-specific adenosine deaminase activity GO:0008251 IBA     metal ion binding GO:0046872 IEA Biological Process     osteoblast differentiation GO:0001649 IMP     hematopoietic progenitor cell differentiation GO:0002244 IMP     somatic diversification of immune receptors via somatic mutation GO:0002566 IDA     adenosine to inosine editing GO:0006382 IBA     adenosine to inosine editing GO:0006382 IDA     adenosine to inosine editing GO:0006382 IMP     adenosine to inosine editing GO:0006382 ISO     RNA processing GO:0006396 IBA     mRNA processing GO:0006397 IEA     protein import into nucleus GO:0006606 ISO     protein export from nucleus GO:0006611 ISO     apoptotic process GO:0006915 IMP     response to virus GO:0009615 ISO     response to virus GO:0009615 ISS     base conversion or substitution editing GO:0016553 ISO     erythrocyte differentiation GO:0030218 IMP     pre-miRNA processing GO:0031054 ISO     miRNA processing GO:0035196 IMP     response to interferon-alpha GO:0035455 ISO     response to interferon-alpha GO:0035455 ISS     negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 IMP     negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 ISO     positive regulation of viral genome replication GO:0045070 IMP     positive regulation of viral genome replication GO:0045070 ISO     innate immune response GO:0045087 IEA     defense response to virus GO:0051607 IEA     definitive hemopoiesis GO:0060216 IMP     negative regulation of type I interferon-mediated signaling pathway GO:0060339 IMP     hematopoietic stem cell homeostasis GO:0061484 IMP     RISC complex assembly GO:0070922 ISO     hepatocyte apoptotic process GO:0097284 IMP     cellular response to virus GO:0098586 IDA     negative regulation of post-transcriptional gene silencing by regulatory ncRNA GO:1900369 IMP     negative regulation of hepatocyte apoptotic process GO:1903944 IMP Subcellular Localization     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     nucleolus GO:0005730 IBA     nucleolus GO:0005730 IDA     nucleolus GO:0005730 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISO     nuclear speck GO:0016607 ISO     supraspliceosomal complex GO:0044530 ISO     supraspliceosomal complex GO:0044530 ISS