Gene description for DPP10
Gene name dipeptidyl-peptidase 10 (non-functional)
Gene symbol DPP10
Other names/aliases DPL2
DPPY
DPRP-3
DPRP3
Species Homo sapiens
 Database cross references - DPP10
ExoCarta ExoCarta_57628
Entrez Gene 57628
HGNC 20823
MIM 608209
UniProt Q8N608  
 DPP10 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for DPP10
Molecular Function
    serine-type peptidase activity GO:0008236 IEA
    dipeptidyl-peptidase activity GO:0008239 IDA
    potassium channel regulator activity GO:0015459 ISS
Biological Process
    protein localization to plasma membrane GO:0072659 ISS
    positive regulation of establishment of protein localization to plasma membrane GO:0090004 IDA
    regulation of potassium ion transmembrane transport GO:1901379 ISS
    proteolysis GO:0006508 IEA
Subcellular Localization
    plasma membrane GO:0005886 ISS
    membrane GO:0016020 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified DPP10 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for DPP10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DPP10 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here