Gene description for VAT1L
Gene name vesicle amine transport 1-like
Gene symbol VAT1L
Other names/aliases -
Species Homo sapiens
 Database cross references - VAT1L
ExoCarta ExoCarta_57687
Vesiclepedia VP_57687
Entrez Gene 57687
HGNC 29315
UniProt Q9HCJ6  
 VAT1L identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
 Gene ontology annotations for VAT1L
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    oxidoreductase activity GO:0016491 IEA
 Experiment description of studies that identified VAT1L in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for VAT1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 UFSP2 55325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SLC9A6 10479
Affinity Capture-MS Homo sapiens
4 ST6GALNAC1  
Affinity Capture-MS Homo sapiens
5 PIBF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 C11orf24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 CREBBP  
Two-hybrid Homo sapiens
8 UBXN2B  
Two-hybrid Homo sapiens
9 SERPIND1 3053
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which VAT1L is involved
No pathways found





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