Gene description for VAT1L
Gene name
vesicle amine transport 1-like
Gene symbol
VAT1L
Other names/aliases
-
Species
Homo sapiens
Database cross references - VAT1L
ExoCarta
ExoCarta_57687
Vesiclepedia
VP_57687
Entrez Gene
57687
HGNC
29315
UniProt
Q9HCJ6
VAT1L identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells
36408942
Neuroblastoma cells
25944692
Gene ontology annotations for VAT1L
Experiment description of studies that identified VAT1L in sEVs
1
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
Protein-protein interactions for VAT1L
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
APP
351
Reconstituted Complex
Homo sapiens
2
UFSP2
55325
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
SLC9A6
10479
Affinity Capture-MS
Homo sapiens
4
ST6GALNAC1
Affinity Capture-MS
Homo sapiens
5
PIBF1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
C11orf24
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
CREBBP
Two-hybrid
Homo sapiens
8
UBXN2B
Two-hybrid
Homo sapiens
9
SERPIND1
3053
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which VAT1L is involved
No pathways found