Gene description for Hist2h2ab
Gene name histone cluster 2, H2ab
Gene symbol Hist2h2ab
Other names/aliases EG621893
H2a-613a
Species Mus musculus
 Database cross references - Hist2h2ab
ExoCarta ExoCarta_621893
Entrez Gene 621893
UniProt Q64522  
 Hist2h2ab identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Hist2h2ab
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleosome GO:0000786 IEA
    chromosome GO:0005694 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Hist2h2ab in exosomes
1
Experiment ID 264
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Hist2h2ab
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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