Gene description for Hspd1
Gene name	heat shock protein 1 (chaperonin)
Gene symbol	Hspd1
Other names/aliases	Hsp60 Hspd1-30p
Species	Rattus norvegicus
Database cross references - Hspd1
ExoCarta	ExoCarta_63868
Vesiclepedia	VP_63868
Entrez Gene	63868
UniProt	P63039
Hspd1 identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Hspd1

Molecular Function     lipopolysaccharide binding GO:0001530 ISO     p53 binding GO:0002039 ISO     double-stranded RNA binding GO:0003725 ISO     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     high-density lipoprotein particle binding GO:0008035 ISO     isomerase activity GO:0016853 IEA     enzyme binding GO:0019899 ISO     ubiquitin protein ligase binding GO:0031625 ISO     apolipoprotein binding GO:0034185 ISO     apolipoprotein A-I binding GO:0034186 ISO     protein-containing complex binding GO:0044877 IPI     protein-folding chaperone binding GO:0051087 IBA     protein-folding chaperone binding GO:0051087 ISO     modification-dependent protein binding GO:0140030 IPI     cysteine-type endopeptidase activator activity GO:0140608 ISO     ATP-dependent protein folding chaperone GO:0140662 IEA Biological Process     response to hypoxia GO:0001666 IEP     MyD88-dependent toll-like receptor signaling pathway GO:0002755 ISO     positive regulation of T cell mediated immune response to tumor cell GO:0002842 ISO     response to ischemia GO:0002931 IEP     protein folding GO:0006457 IBA     'de novo' protein folding GO:0006458 IC     response to unfolded protein GO:0006986 ISO     apoptotic mitochondrial changes GO:0008637 IBA     apoptotic mitochondrial changes GO:0008637 IMP     response to cold GO:0009409 ISS     response to xenobiotic stimulus GO:0009410 IEP     response to organic cyclic compound GO:0014070 IEP     response to activity GO:0014823 IEP     response to lipopolysaccharide GO:0032496 IEP     positive regulation of interferon-alpha production GO:0032727 IBA     positive regulation of interferon-alpha production GO:0032727 ISO     positive regulation of interferon-alpha production GO:0032727 ISO     positive regulation of type II interferon production GO:0032729 IBA     positive regulation of type II interferon production GO:0032729 ISO     positive regulation of type II interferon production GO:0032729 ISO     positive regulation of interleukin-10 production GO:0032733 ISO     positive regulation of interleukin-12 production GO:0032735 ISO     positive regulation of interleukin-6 production GO:0032755 IBA     positive regulation of interleukin-6 production GO:0032755 IMP     positive regulation of interleukin-6 production GO:0032755 ISO     positive regulation of tumor necrosis factor production GO:0032760 IMP     response to ATP GO:0033198 IEP     mitochondrial unfolded protein response GO:0034514 IBA     cellular response to heat GO:0034605 IEP     protein refolding GO:0042026 ISO     B cell proliferation GO:0042100 ISO     T cell activation GO:0042110 IBA     T cell activation GO:0042110 ISO     B cell activation GO:0042113 ISO     response to cocaine GO:0042220 IEP     response to hydrogen peroxide GO:0042542 IEP     positive regulation of macrophage activation GO:0043032 ISO     negative regulation of apoptotic process GO:0043066 IMP     negative regulation of apoptotic process GO:0043066 ISO     negative regulation of neuron apoptotic process GO:0043524 IMP     response to estrogen GO:0043627 IEP     adhesion of symbiont to host GO:0044406 ISO     protein import into mitochondrial intermembrane space GO:0045041 IBA     isotype switching to IgG isotypes GO:0048291 ISO     protein stabilization GO:0050821 ISO     positive regulation of T cell activation GO:0050870 IBA     positive regulation of T cell activation GO:0050870 ISO     response to glucocorticoid GO:0051384 IEP     negative regulation of apoptotic process in bone marrow cell GO:0071866 IMP     cellular response to interleukin-7 GO:0098761 ISO     negative regulation of execution phase of apoptosis GO:1900118 ISO     positive regulation of execution phase of apoptosis GO:1900119 ISO     negative regulation of reactive oxygen species biosynthetic process GO:1903427 IMP     response to resveratrol GO:1904638 IEP Subcellular Localization     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISO     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 ISO     mitochondrion GO:0005739 ISO     mitochondrial inner membrane GO:0005743 IBA     mitochondrial inner membrane GO:0005743 IDA     mitochondrial matrix GO:0005759 IBA     mitochondrial matrix GO:0005759 ISO     mitochondrial matrix GO:0005759 ISO     early endosome GO:0005769 ISO     peroxisomal matrix GO:0005782 IDA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 ISO     clathrin-coated pit GO:0005905 ISO     cell surface GO:0009986 IDA     cell surface GO:0009986 ISO     membrane GO:0016020 ISO     mitochondrial crista GO:0030061 IDA     coated vesicle GO:0030135 ISO     secretory granule GO:0030141 IDA     secretory granule GO:0030141 ISO     Golgi cisterna GO:0031985 IDA     protein-containing complex GO:0032991 ISO     protein-containing complex GO:0032991 ISS     zymogen granule GO:0042588 IDA     intracellular membrane-bounded organelle GO:0043231 ISO     lipopolysaccharide receptor complex GO:0046696 ISO     extracellular exosome GO:0070062 ISO     sperm midpiece GO:0097225 ISO     sperm plasma membrane GO:0097524 ISO     migrasome GO:0140494 ISO