Gene description for Basp1
Gene name brain abundant, membrane attached signal protein 1
Gene symbol Basp1
Other names/aliases NAP22
Species Rattus norvegicus
 Database cross references - Basp1
ExoCarta ExoCarta_64160
Entrez Gene 64160
UniProt Q05175  
 Basp1 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Basp1
Molecular Function
    transcription corepressor activity GO:0003714 ISS
    protein domain specific binding GO:0019904 ISO
    calmodulin binding GO:0005516 IEA
    transcription regulatory region DNA binding GO:0044212 ISS
Biological Process
    substantia nigra development GO:0021762 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISS
    glomerular visceral epithelial cell differentiation GO:0072112 ISO
Subcellular Localization
    growth cone GO:0030426 IEA
    nuclear speck GO:0016607 ISS
    extracellular exosome GO:0070062 ISO
    plasma membrane GO:0005886 ISO
    COP9 signalosome GO:0008180 ISO
    vesicle GO:0031982 ISO
    cell junction GO:0030054 ISO
    cytoplasm GO:0005737 ISS
    nucleus GO:0005634 ISS
 Experiment description of studies that identified Basp1 in exosomes
1
Experiment ID 192
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
CD63|CD81|FLOT
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Basp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Basp1 is involved
No pathways found





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