Gene description for Basp1
Gene name brain abundant, membrane attached signal protein 1
Gene symbol Basp1
Other names/aliases NAP22
Species Rattus norvegicus
 Database cross references - Basp1
ExoCarta ExoCarta_64160
Vesiclepedia VP_64160
Entrez Gene 64160
UniProt Q05175  
 Basp1 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Basp1
Molecular Function
    transcription cis-regulatory region binding GO:0000976 IBA
    transcription cis-regulatory region binding GO:0000976 IEA
    transcription cis-regulatory region binding GO:0000976 ISO
    transcription cis-regulatory region binding GO:0000976 ISS
    transcription corepressor activity GO:0003714 IBA
    transcription corepressor activity GO:0003714 IEA
    transcription corepressor activity GO:0003714 ISO
    transcription corepressor activity GO:0003714 ISS
    calmodulin binding GO:0005516 IEA
    calmodulin binding GO:0005516 ISO
    protein domain specific binding GO:0019904 IEA
    protein domain specific binding GO:0019904 ISO
Biological Process
    substantia nigra development GO:0021762 ISO
    negative regulation of DNA-templated transcription GO:0045892 IBA
    negative regulation of DNA-templated transcription GO:0045892 IEA
    negative regulation of DNA-templated transcription GO:0045892 ISO
    negative regulation of DNA-templated transcription GO:0045892 ISS
    protein homooligomerization GO:0051260 IEA
    protein homooligomerization GO:0051260 ISO
    podocyte differentiation GO:0072112 IEA
    podocyte differentiation GO:0072112 ISO
    supramolecular fiber organization GO:0097435 IEA
    supramolecular fiber organization GO:0097435 ISO
Subcellular Localization
    chromatin GO:0000785 IEA
    chromatin GO:0000785 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    COP9 signalosome GO:0008180 IEA
    COP9 signalosome GO:0008180 ISO
    nuclear matrix GO:0016363 IEA
    nuclear matrix GO:0016363 ISO
    PML body GO:0016605 IEA
    PML body GO:0016605 ISO
    nuclear speck GO:0016607 IEA
    nuclear speck GO:0016607 ISO
    nuclear speck GO:0016607 ISS
    cell junction GO:0030054 IEA
    cell junction GO:0030054 ISO
    growth cone GO:0030426 IEA
 Experiment description of studies that identified Basp1 in exosomes
1
Experiment ID 192
MISEV standards
CEM
Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Basp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Snca  
Affinity Capture-MS Rattus norvegicus
2 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
3 Park7 117287
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



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