Gene description for LINC00657
Gene name long intergenic non-protein coding RNA 657
Gene symbol LINC00657
Other names/aliases -
Species Homo sapiens
 Database cross references - LINC00657
ExoCarta ExoCarta_647979
Vesiclepedia VP_647979
Entrez Gene 647979
HGNC 44311
 LINC00657 identified in sEVs derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for LINC00657
Molecular Function
    protein sequestering activity GO:0140311 TAS
Biological Process
    regulation of mRNA stability GO:0043488 TAS
 Experiment description of studies that identified LINC00657 in sEVs
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule lincRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for LINC00657
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MOV10 4343
Affinity Capture-RNA Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 NXF1 10482
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which LINC00657 is involved
No pathways found





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