Gene description for ACTR3C
Gene name ARP3 actin-related protein 3 homolog C (yeast)
Gene symbol ACTR3C
Other names/aliases ARP11
Species Homo sapiens
 Database cross references - ACTR3C
ExoCarta ExoCarta_653857
Entrez Gene 653857
HGNC 37282
UniProt Q9C0K3  
 ACTR3C identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 22723089    
 Gene ontology annotations for ACTR3C
Molecular Function
    ATP binding GO:0005524 IEA
    molecular_function GO:0003674 ND
    actin binding GO:0003779 IEA
Biological Process
    biological_process GO:0008150 ND
    Arp2/3 complex-mediated actin nucleation GO:0034314 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    Arp2/3 protein complex GO:0005885 IEA
 Experiment description of studies that identified ACTR3C in exosomes
1
Experiment ID 139
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90|RAB5
EV Cytosolic markers
LAMP2|CD9
EV Membrane markers
HSP90B1
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors Hosseini-Beheshti E, Guns ES.
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
 Protein-protein interactions for ACTR3C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ACTR3C is involved
No pathways found





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