Gene description for SLC6A13
Gene name solute carrier family 6 (neurotransmitter transporter), member 13
Gene symbol SLC6A13
Other names/aliases GAT-2
GAT2
GAT3
Species Homo sapiens
 Database cross references - SLC6A13
ExoCarta ExoCarta_6540
Entrez Gene 6540
HGNC 11046
MIM 615097
UniProt Q9NSD5  
 SLC6A13 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC6A13
Molecular Function
    neurotransmitter:sodium symporter activity GO:0005328 IEA
    gamma-aminobutyric acid:sodium symporter activity GO:0005332 IEA
Biological Process
    gamma-aminobutyric acid transport GO:0015812 IEA
    neurotransmitter secretion GO:0007269 TAS
    synaptic transmission GO:0007268 TAS
    transmembrane transport GO:0055085 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 IEA
    extracellular exosome GO:0070062 IDA
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified SLC6A13 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC6A13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC6A13 is involved
PathwayEvidenceSource
Na+/Cl- dependent neurotransmitter transporters TAS Reactome
Reuptake of GABA TAS Reactome





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