Gene description for SLC34A1
Gene name solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
Gene symbol SLC34A1
Other names/aliases FRTS2
NAPI-3
NPHLOP1
NPT2
NPTIIa
SLC11
SLC17A2
Species Homo sapiens
 Database cross references - SLC34A1
ExoCarta ExoCarta_6569
Vesiclepedia VP_6569
Entrez Gene 6569
HGNC 11019
MIM 182309
UniProt Q06495  
 SLC34A1 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SLC34A1
Molecular Function
    sodium:phosphate symporter activity GO:0005436 IBA
    sodium:phosphate symporter activity GO:0005436 IDA
    sodium:phosphate symporter activity GO:0005436 IMP
    sodium:phosphate symporter activity GO:0005436 TAS
    protein binding GO:0005515 IPI
    PDZ domain binding GO:0030165 IEA
    identical protein binding GO:0042802 IEA
    protein-containing complex binding GO:0044877 IEA
Biological Process
    ossification GO:0001503 IEA
    kidney development GO:0001822 IEA
    phosphate ion transport GO:0006817 IDA
    glycoprotein metabolic process GO:0009100 IEA
    response to xenobiotic stimulus GO:0009410 IEA
    response to lead ion GO:0010288 IDA
    cellular response to phosphate starvation GO:0016036 IEA
    intracellular phosphate ion homeostasis GO:0030643 IBA
    response to magnesium ion GO:0032026 IEA
    response to estradiol GO:0032355 IEA
    response to vitamin A GO:0033189 IEA
    phosphate ion transmembrane transport GO:0035435 IEA
    response to potassium ion GO:0035864 IEA
    indole metabolic process GO:0042431 IEA
    sodium-dependent phosphate transport GO:0044341 IBA
    positive regulation of membrane potential GO:0045838 IEA
    response to cadmium ion GO:0046686 IDA
    response to mercury ion GO:0046689 IDA
    phosphate ion homeostasis GO:0055062 IDA
    response to growth hormone GO:0060416 IEA
    cellular response to metal ion GO:0071248 IEA
    cellular response to parathyroid hormone stimulus GO:0071374 IEA
    tricarboxylic acid metabolic process GO:0072350 IEA
    cellular response to staurosporine GO:0072734 IEA
    response to thyroid hormone GO:0097066 IEA
    dentinogenesis GO:0097187 IEA
    sodium ion import across plasma membrane GO:0098719 IEA
    gentamycin metabolic process GO:1901128 IEA
    response to peptide GO:1901652 IEA
    arsenate ion transmembrane transport GO:1901684 IEA
    positive regulation of sodium-dependent phosphate transport GO:2000120 IEA
    positive regulation of phosphate transmembrane transport GO:2000187 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    endosome GO:0005768 IEA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IMP
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    brush border GO:0005903 IBA
    cell surface GO:0009986 IEA
    apical plasma membrane GO:0016324 IBA
    apical plasma membrane GO:0016324 IDA
    nuclear speck GO:0016607 IDA
    brush border membrane GO:0031526 ISS
    brush border membrane GO:0031526 NAS
    vesicle GO:0031982 IBA
    perinuclear region of cytoplasm GO:0048471 IEA
    mitotic spindle GO:0072686 IDA
 Experiment description of studies that identified SLC34A1 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC34A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml



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