Gene description for Plbd1
Gene name phospholipase B domain containing 1
Gene symbol Plbd1
Other names/aliases 1100001H23Rik
Species Mus musculus
 Database cross references - Plbd1
ExoCarta ExoCarta_66857
Entrez Gene 66857
UniProt Q8VCI0  
 Plbd1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Plbd1
Molecular Function
    Cys-tRNA(Pro) hydrolase activity GO:0043907 IEA
    butyrolactone hydrolase activity GO:0018734 IEA
    3,4-dihydrocoumarin hydrolase activity GO:0018733 IEA
    Ser(Gly)-tRNA(Ala) hydrolase activity GO:0043908 IEA
    phospholipase activity GO:0004620 IEA
    sulfolactone hydrolase activity GO:0018732 IEA
    lipase activity GO:0016298 IEA
    retinyl-palmitate esterase activity GO:0050253 IEA
    methyl salicylate esterase activity GO:0080031 IEA
    1-oxa-2-oxocycloheptane lactonase activity GO:0018731 IEA
    methyl jasmonate esterase activity GO:0080032 IEA
    methyl indole-3-acetate esterase activity GO:0080030 IEA
    L-ascorbate 6-phosphate lactonase activity GO:0035460 IEA
    all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity GO:0047376 IEA
    prenylcysteine methylesterase activity GO:0010296 IEA
    mannosyl-oligosaccharide 1,6-alpha-mannosidase activity GO:0052767 IEA
    molecular_function GO:0003674 ND
    mannosyl-oligosaccharide 1,3-alpha-mannosidase activity GO:0052768 IEA
    Ala-tRNA(Pro) hydrolase activity GO:0043906 IEA
    Ser-tRNA(Thr) hydrolase activity GO:0043905 IEA
    hydrolase activity GO:0016787 IEA
    endosulfan lactone lactonase activity GO:0034892 IEA
Biological Process
    lipid catabolic process GO:0016042 IEA
    biological_process GO:0008150 ND
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
    lysosome GO:0005764 IEA
 Experiment description of studies that identified Plbd1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Plbd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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