Gene description for Cybb
Gene name	cytochrome b-245, beta polypeptide
Gene symbol	Cybb
Other names/aliases	C88302 CGD91-phox Cgd Cyd Nox2 gp91-1 gp91phox
Species	Mus musculus
Database cross references - Cybb
ExoCarta	ExoCarta_13058
Entrez Gene	13058
UniProt	Q61093
Cybb identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846

Gene ontology annotations for Cybb

Molecular Function     electron carrier activity GO:0009055 ISO     superoxide-generating NADPH oxidase activity GO:0016175 ISO     malolactic enzyme activity GO:0043883 IEA     flavin adenine dinucleotide binding GO:0050660 ISO     reduced coenzyme F420 dehydrogenase activity GO:0043738 IEA     epoxyqueuosine reductase activity GO:0052693 IEA     voltage-gated ion channel activity GO:0005244 IEA     N-ethylmaleimide reductase activity GO:0008748 IEA     metal ion binding GO:0046872 IEA     oxidoreductase activity GO:0016491 IEA     protein binding GO:0005515 IPI     protein heterodimerization activity GO:0046982 ISO     NADPH:sulfur oxidoreductase activity GO:0043914 IEA     heme binding GO:0020037 ISO     sulfur oxygenase reductase activity GO:0043826 IEA Biological Process     response to drug GO:0042493 ISO     transport GO:0006810 IEA     innate immune response GO:0045087 ISO     ion transport GO:0006811 IEA     oxidation-reduction process GO:0055114 ISO     regulation of ion transmembrane transport GO:0034765 IEA     hydrogen peroxide biosynthetic process GO:0050665 IMP     inflammatory response GO:0006954 IMP     respiratory burst GO:0045730 ISO     superoxide metabolic process GO:0006801 ISO     superoxide anion generation GO:0042554 ISO Subcellular Localization     neuronal cell body GO:0043025 ISO     endoplasmic reticulum GO:0005783 ISO     NADPH oxidase complex GO:0043020 ISO     integral component of plasma membrane GO:0005887 ISO     mitochondrion GO:0005739 IDA     integral component of membrane GO:0016021 IEA     rough endoplasmic reticulum GO:0005791 ISO     intracellular GO:0005622 ISO     plasma membrane GO:0005886 ISO     cytoplasm GO:0005737 IDA     dendrite GO:0030425 ISO     membrane GO:0016020 IEA     Golgi apparatus GO:0005794 ISO