Gene description for Eif2s2
Gene name eukaryotic translation initiation factor 2, subunit 2 (beta)
Gene symbol Eif2s2
Other names/aliases 2810026E11Rik
38kDa
AA408636
AA571381
AA986487
AW822225
D2Ertd303e
EIF2
EIF2B
Species Mus musculus
 Database cross references - Eif2s2
ExoCarta ExoCarta_67204
Entrez Gene 67204
UniProt Q99L45  
 Eif2s2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Eif2s2
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    translation initiation factor activity GO:0003743 ISO
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translational initiation GO:0006413 ISO
    male germ cell proliferation GO:0002176 IMP
    in utero embryonic development GO:0001701 IMP
    male gonad development GO:0008584 IMP
    translation GO:0006412 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Eif2s2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Eif2s2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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