Gene description for Eif1
Gene name eukaryotic translation initiation factor 1
Gene symbol Eif1
Other names/aliases Sui1-rs1
Species Mus musculus
 Database cross references - Eif1
ExoCarta ExoCarta_20918
Entrez Gene 20918
UniProt P48024  
 Eif1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Eif1
Molecular Function
    molecular_function GO:0003674 ND
    translation initiation factor activity GO:0003743 IEA
Biological Process
    dosage compensation by inactivation of X chromosome GO:0009048 IMP
    translational initiation GO:0006413 IEA
    translation GO:0006412 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Eif1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Eif1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eif1 is involved
No pathways found





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