Gene description for Eif3b
Gene name eukaryotic translation initiation factor 3, subunit B
Gene symbol Eif3b
Other names/aliases AL033316
AL033334
AL033369
AW208965
D5Wsu45e
EIF3-ETA
EIF3-P110
EIF3-P116
Eif3s9
PRT1
Species Mus musculus
 Database cross references - Eif3b
ExoCarta ExoCarta_27979
Entrez Gene 27979
UniProt Q8JZQ9  
 Eif3b identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Eif3b
Molecular Function
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 IEA
    translation initiation factor binding GO:0031369 IEA
    translation initiation factor activity GO:0003743 ISO
    protein binding GO:0005515 IPI
Biological Process
    translation GO:0006412 IEA
    regulation of translational initiation GO:0006446 ISO
    translational initiation GO:0006413 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541 IDA
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Eif3b in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Eif3b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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