Gene description for Eif3b
Gene name eukaryotic translation initiation factor 3, subunit B
Gene symbol Eif3b
Other names/aliases AL033316
Species Mus musculus
 Database cross references - Eif3b
ExoCarta ExoCarta_27979
Entrez Gene 27979
UniProt Q8JZQ9  
 Eif3b identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Eif3b
Molecular Function
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 IEA
    translation initiation factor binding GO:0031369 IEA
    translation initiation factor activity GO:0003743 ISO
    protein binding GO:0005515 IPI
Biological Process
    translation GO:0006412 IEA
    regulation of translational initiation GO:0006446 ISO
    translational initiation GO:0006413 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541 IDA
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Eif3b in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Eif3b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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