Gene description for Arpc4
Gene name actin related protein 2/3 complex, subunit 4
Gene symbol Arpc4
Other names/aliases 20kDa
5330419I20Rik
AI327076
p20-Arc
Species Mus musculus
 Database cross references - Arpc4
ExoCarta ExoCarta_68089
Entrez Gene 68089
UniProt P59999  
 Arpc4 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Arpc4
Molecular Function
    actin filament binding GO:0051015 ISO
    protein binding, bridging GO:0030674 ISO
    enzyme binding GO:0019899 ISO
    structural constituent of cytoskeleton GO:0005200 ISO
    actin binding GO:0003779 IEA
Biological Process
    actin filament polymerization GO:0030041 IEA
    Arp2/3 complex-mediated actin nucleation GO:0034314 ISO
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    Arp2/3 protein complex GO:0005885 TAS
    actin cytoskeleton GO:0015629 IEA
    cell projection GO:0042995 IEA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Arpc4 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Arpc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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