Gene description for Arpc4
Gene name actin related protein 2/3 complex, subunit 4
Gene symbol Arpc4
Other names/aliases 20kDa
5330419I20Rik
AI327076
p20-Arc
Species Mus musculus
 Database cross references - Arpc4
ExoCarta ExoCarta_68089
Entrez Gene 68089
UniProt P59999  
 Arpc4 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Arpc4
Molecular Function
    actin filament binding GO:0051015 ISO
    protein binding, bridging GO:0030674 ISO
    enzyme binding GO:0019899 ISO
    structural constituent of cytoskeleton GO:0005200 ISO
    actin binding GO:0003779 IEA
Biological Process
    actin filament polymerization GO:0030041 IEA
    Arp2/3 complex-mediated actin nucleation GO:0034314 ISO
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    Arp2/3 protein complex GO:0005885 TAS
    actin cytoskeleton GO:0015629 IEA
    cell projection GO:0042995 IEA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Arpc4 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Arpc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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