Gene description for Eif3h
Gene name eukaryotic translation initiation factor 3, subunit H
Gene symbol Eif3h
Other names/aliases 1110008A16Rik
40kD
9430017H16Rik
EIF3-P40
EIF3-gamma
Eif3s3
Species Mus musculus
 Database cross references - Eif3h
ExoCarta ExoCarta_68135
Entrez Gene 68135
UniProt Q91WK2  
 Eif3h identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
Mast cells 17486113    
 Gene ontology annotations for Eif3h
Molecular Function
    protein complex binding GO:0032403 ISO
    translation initiation factor activity GO:0003743 ISO
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translation GO:0006412 IEA
    translational initiation GO:0006413 ISO
Subcellular Localization
    protein complex GO:0043234 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
    eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541 IDA
    cytoplasm GO:0005737 IEA
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Eif3h in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Eif3h
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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