Gene description for Ndufb4
Gene name NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
Gene symbol Ndufb4
Other names/aliases 0610006N12Rik
1300010H20Rik
Species Mus musculus
 Database cross references - Ndufb4
ExoCarta ExoCarta_68194
Entrez Gene 68194
UniProt Q9CQC7  
 Ndufb4 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ndufb4
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    response to oxidative stress GO:0006979 ISO
Subcellular Localization
    nuclear membrane GO:0031965 ISO
    extracellular exosome GO:0070062 ISO
    mitochondrial respiratory chain complex I GO:0005747 ISO
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Ndufb4 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ndufb4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ndufb4 is involved
PathwayEvidenceSource
Respiratory electron transport IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here