Gene description for Pgm2
Gene name phosphoglucomutase 2
Gene symbol Pgm2
Other names/aliases 2610020G18Rik
AA407108
AI098105
Pgm-2
Pgm1
Species Mus musculus
 Database cross references - Pgm2
ExoCarta ExoCarta_72157
Vesiclepedia VP_72157
Entrez Gene 72157
UniProt Q9D0F9  
 Pgm2 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
Pancreatic cells 19351151    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Pgm2
Molecular Function
    intramolecular transferase activity, phosphotransferases GO:0016868 IEA
    metal ion binding GO:0046872 IEA
    phosphoglucomutase activity GO:0004614 ISO
    magnesium ion binding GO:0000287 IEA
    isomerase activity GO:0016853 IEA
Biological Process
    glucose metabolic process GO:0006006 IDA
    organic substance metabolic process GO:0071704 IEA
    glycogen biosynthetic process GO:0005978 IBA
    galactose catabolic process GO:0019388 IBA
    carbohydrate metabolic process GO:0005975 IEA
Subcellular Localization
    actin cytoskeleton GO:0015629 ISO
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 IBA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Pgm2 in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 188
MISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Pgm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgm2 is involved
PathwayEvidenceSource
Galactose catabolism IEA Reactome
Glycogen breakdown (glycogenolysis) IEA Reactome
Glycogen synthesis IEA Reactome





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