Gene description for WNT8B
Gene name wingless-type MMTV integration site family, member 8B
Gene symbol WNT8B
Other names/aliases -
Species Homo sapiens
 Database cross references - WNT8B
ExoCarta ExoCarta_7479
Vesiclepedia VP_7479
Entrez Gene 7479
HGNC 12789
MIM 601396
UniProt Q93098  
 WNT8B identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for WNT8B
Molecular Function
    frizzled binding GO:0005109 IBA
    cytokine activity GO:0005125 IBA
    receptor ligand activity GO:0048018 IDA
Biological Process
    signal transduction GO:0007165 TAS
    gastrulation GO:0007369 ISS
    nervous system development GO:0007399 TAS
    neuron differentiation GO:0030182 IBA
    neuron differentiation GO:0030182 ISS
    response to estradiol GO:0032355 NAS
    response to retinoic acid GO:0032526 NAS
    cell fate commitment GO:0045165 IBA
    determination of dorsal identity GO:0048263 ISS
    canonical Wnt signaling pathway GO:0060070 IBA
    canonical Wnt signaling pathway GO:0060070 IDA
    cellular response to retinoic acid GO:0071300 ISS
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
 Experiment description of studies that identified WNT8B in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for WNT8B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SDR9C7  
Affinity Capture-MS Homo sapiens
2 ALOXE3  
Affinity Capture-MS Homo sapiens
3 BPIFA1 51297
Affinity Capture-MS Homo sapiens
4 HAL 3034
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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