Gene description for CACNA1S
Gene name	calcium channel, voltage-dependent, L type, alpha 1S subunit
Gene symbol	CACNA1S
Other names/aliases	CACNL1A3 CCHL1A3 Cav1.1 HOKPP HOKPP1 MHS5 TTPP1 hypoPP
Species	Homo sapiens
Database cross references - CACNA1S
ExoCarta	ExoCarta_779
Vesiclepedia	VP_779
Entrez Gene	779
HGNC	1397
MIM	114208
UniProt	Q13698
CACNA1S identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for CACNA1S

Molecular Function     voltage-gated calcium channel activity GO:0005245 IDA     voltage-gated calcium channel activity GO:0005245 IMP     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IEA     high voltage-gated calcium channel activity GO:0008331 IBA     high voltage-gated calcium channel activity GO:0008331 IDA     small molecule binding GO:0036094 EXP     metal ion binding GO:0046872 IEA     molecular function activator activity GO:0140677 EXP Biological Process     skeletal system development GO:0001501 IEA     extraocular skeletal muscle development GO:0002074 IEA     calcium ion transport GO:0006816 IDA     muscle contraction GO:0006936 IMP     striated muscle contraction GO:0006941 IEA     endoplasmic reticulum organization GO:0007029 IEA     myoblast fusion GO:0007520 IEA     neuromuscular junction development GO:0007528 IEA     skeletal muscle adaptation GO:0043501 IEA     positive regulation of muscle contraction GO:0045933 NAS     skeletal muscle fiber development GO:0048741 IEA     release of sequestered calcium ion into cytosol GO:0051209 IMP     calcium ion transmembrane transport GO:0070588 NAS     cellular response to caffeine GO:0071313 ISS     calcium ion import across plasma membrane GO:0098703 IBA Subcellular Localization     cytoplasm GO:0005737 IDA     plasma membrane GO:0005886 IDA     voltage-gated calcium channel complex GO:0005891 IBA     voltage-gated calcium channel complex GO:0005891 IDA     sarcoplasmic reticulum GO:0016529 IEA     T-tubule GO:0030315 IDA     T-tubule GO:0030315 IMP     T-tubule GO:0030315 NAS     I band GO:0031674 IDA     L-type voltage-gated calcium channel complex GO:1990454 ISO     L-type voltage-gated calcium channel complex GO:1990454 ISS