Gene description for Fabp4
Gene name fatty acid binding protein 4, adipocyte
Gene symbol Fabp4
Other names/aliases Albp
aP2
Species Rattus norvegicus
 Database cross references - Fabp4
ExoCarta ExoCarta_79451
Entrez Gene 79451
 Fabp4 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Fabp4
Molecular Function
    fatty acid binding GO:0005504 TAS
    transporter activity GO:0005215 IEA
    lipid binding GO:0008289 IEA
    protein binding GO:0005515 IPI
Biological Process
    brown fat cell differentiation GO:0050873 ISO
    response to drug GO:0042493 IEP
    cytokine production GO:0001816 ISO
    fatty acid metabolic process GO:0006631 IDA
    response to glucocorticoid GO:0051384 IEP
    white fat cell differentiation GO:0050872 ISO
    cellular response to lithium ion GO:0071285 ISO
    positive regulation of cell proliferation GO:0008284 IMP
    cholesterol homeostasis GO:0042632 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISO
    positive regulation of inflammatory response GO:0050729 ISO
    negative regulation of protein kinase activity GO:0006469 ISO
    transport GO:0006810 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytosol GO:0005829 IDA
    cytoplasm GO:0005737 ISO
    lipid particle GO:0005811 TAS
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Fabp4 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Fabp4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fabp4 is involved
No pathways found





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