Gene description for ZDHHC14
Gene name zinc finger, DHHC-type containing 14
Gene symbol ZDHHC14
Other names/aliases NEW1CP
Species Homo sapiens
 Database cross references - ZDHHC14
ExoCarta ExoCarta_79683
Vesiclepedia VP_79683
Entrez Gene 79683
HGNC 20341
UniProt Q8IZN3  
 ZDHHC14 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZDHHC14
Molecular Function
    palmitoyltransferase activity GO:0016409 IDA
    protein-cysteine S-palmitoyltransferase activity GO:0019706 IBA
    protein-cysteine S-palmitoyltransferase activity GO:0019706 IC
Biological Process
    protein targeting to membrane GO:0006612 IBA
    peptidyl-L-cysteine S-palmitoylation GO:0018230 IMP
    protein palmitoylation GO:0018345 IDA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    Golgi apparatus GO:0005794 IBA
    Golgi cisterna membrane GO:0032580 IEA
 Experiment description of studies that identified ZDHHC14 in sEVs
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZDHHC14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
2 GOLGA7 51125
Co-purification Homo sapiens
View the network image/svg+xml
 Pathways in which ZDHHC14 is involved
No pathways found





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