Gene description for CFAP43
Gene name cilia and flagella associated protein 43
Gene symbol CFAP43
Other names/aliases C10orf79
WDR96
bA373N18.2
Species Homo sapiens
 Database cross references - CFAP43
ExoCarta ExoCarta_80217
Vesiclepedia VP_80217
Entrez Gene 80217
HGNC 26684
UniProt Q8NDM7  
 CFAP43 identified in sEVs derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CFAP43
Biological Process
    cell morphogenesis GO:0000902 IEA
    regulation of cilium beat frequency GO:0003356 ISS
    nucleus organization GO:0006997 IEA
    sperm axoneme assembly GO:0007288 IBA
    sperm axoneme assembly GO:0007288 IMP
    sperm axoneme assembly GO:0007288 ISS
    brain development GO:0007420 IEA
    establishment of localization in cell GO:0051649 IEA
    cilium assembly GO:0060271 IBA
    cerebrospinal fluid circulation GO:0090660 IEA
    mucociliary clearance GO:0120197 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    axoneme GO:0005930 IBA
    axoneme GO:0005930 ISS
    9+2 motile cilium GO:0097729 IEA
 Experiment description of studies that identified CFAP43 in sEVs
1
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for CFAP43
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAE 7531
Affinity Capture-MS Homo sapiens
2 CUL7 9820
Affinity Capture-MS Homo sapiens
3 SEC13 6396
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CFAP43 is involved
No pathways found





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