Gene description for Senp3
Gene name SUMO/sentrin specific peptidase 3
Gene symbol Senp3
Other names/aliases AA408656
Smt3ip
Smt3ip1
Species Mus musculus
 Database cross references - Senp3
ExoCarta ExoCarta_80886
Entrez Gene 80886
UniProt Q9EP97  
 Senp3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Senp3
Molecular Function
    hydrolase activity GO:0016787 IEA
    ubiquitin-specific protease activity GO:0004843 IDA
    protein binding GO:0005515 IPI
    cysteine-type peptidase activity GO:0008234 IEA
    peptidase activity GO:0008233 IEA
Biological Process
    protein metabolic process GO:0019538 IDA
    proteolysis GO:0006508 IDA
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IEA
    MLL1 complex GO:0071339 ISO
    nucleolus GO:0005730 ISO
 Experiment description of studies that identified Senp3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Senp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Senp3 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here