Gene description for Vim
Gene name vimentin
Gene symbol Vim
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Vim
ExoCarta ExoCarta_81818
Entrez Gene 81818
UniProt P31000  
 Vim identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Vim
Molecular Function
    protein kinase binding GO:0019901 IPI
    keratin filament binding GO:1990254 ISO
    structural constituent of cytoskeleton GO:0005200 ISS
    double-stranded RNA binding GO:0003725 ISO
    structural molecule activity GO:0005198 TAS
    identical protein binding GO:0042802 ISO
    protein C-terminus binding GO:0008022 ISO
    glycoprotein binding GO:0001948 ISO
    protein phosphatase 2A binding GO:0051721 IDA
    structural constituent of eye lens GO:0005212 ISO
    kinase binding GO:0019900 IPI
    scaffold protein binding GO:0097110 ISO
    protein binding GO:0005515 IPI
Biological Process
    aging GO:0007568 IEP
    positive regulation of glial cell proliferation GO:0060252 IMP
    response to zinc ion GO:0010043 IEP
    response to radiation GO:0009314 IEP
    decidualization GO:0046697 IEP
    regulation of Schwann cell migration GO:1900147 IDA
    Bergmann glial cell differentiation GO:0060020 ISO
    intermediate filament-based process GO:0045103 ISO
    response to selenium ion GO:0010269 IEP
    fat cell differentiation GO:0045444 IEP
    lens fiber cell development GO:0070307 ISO
    negative regulation of neuron projection development GO:0010977 ISO
    SMAD protein signal transduction GO:0060395 ISO
    regulation of axonogenesis GO:0050770 IDA
    skeletal muscle tissue regeneration GO:0043403 IEP
    intermediate filament organization GO:0045109 ISO
    cellular response to fibroblast growth factor stimulus GO:0044344 IEP
    positive regulation of gene expression GO:0010628 ISO
    astrocyte development GO:0014002 ISO
    response to estradiol GO:0032355 IEP
    response to vitamin D GO:0033280 IEP
Subcellular Localization
    axon GO:0030424 IDA
    intermediate filament GO:0005882 ISS
    peroxisome GO:0005777 ISO
    cytosol GO:0005829 ISO
    cytoskeleton GO:0005856 ISO
    cell leading edge GO:0031252 ISO
    type III intermediate filament GO:0045098 TAS
    plasma membrane GO:0005886 ISO
    neuron projection GO:0043005 ISO
    cytoplasm GO:0005737 ISS
    cell projection GO:0042995 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    nuclear matrix GO:0016363 IEA
    cell body GO:0044297 IDA
    extracellular exosome GO:0070062 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Vim in exosomes
Experiment ID 225
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Vim
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DYNLL1 8655
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Vim is involved
No pathways found

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