Gene description for Vim
Gene name vimentin
Gene symbol Vim
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Vim
ExoCarta ExoCarta_81818
Vesiclepedia VP_81818
Entrez Gene 81818
UniProt P31000  
 Vim identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Vim
Molecular Function
    protein kinase binding GO:0019901 IPI
    keratin filament binding GO:1990254 ISO
    structural constituent of cytoskeleton GO:0005200 ISS
    double-stranded RNA binding GO:0003725 ISO
    structural molecule activity GO:0005198 TAS
    identical protein binding GO:0042802 ISO
    protein C-terminus binding GO:0008022 ISO
    glycoprotein binding GO:0001948 ISO
    protein phosphatase 2A binding GO:0051721 IDA
    structural constituent of eye lens GO:0005212 ISO
    kinase binding GO:0019900 IPI
    scaffold protein binding GO:0097110 ISO
    protein binding GO:0005515 IPI
Biological Process
    aging GO:0007568 IEP
    positive regulation of glial cell proliferation GO:0060252 IMP
    response to zinc ion GO:0010043 IEP
    response to radiation GO:0009314 IEP
    decidualization GO:0046697 IEP
    regulation of Schwann cell migration GO:1900147 IDA
    Bergmann glial cell differentiation GO:0060020 ISO
    intermediate filament-based process GO:0045103 ISO
    response to selenium ion GO:0010269 IEP
    fat cell differentiation GO:0045444 IEP
    lens fiber cell development GO:0070307 ISO
    negative regulation of neuron projection development GO:0010977 ISO
    SMAD protein signal transduction GO:0060395 ISO
    regulation of axonogenesis GO:0050770 IDA
    skeletal muscle tissue regeneration GO:0043403 IEP
    intermediate filament organization GO:0045109 ISO
    cellular response to fibroblast growth factor stimulus GO:0044344 IEP
    positive regulation of gene expression GO:0010628 ISO
    astrocyte development GO:0014002 ISO
    response to estradiol GO:0032355 IEP
    response to vitamin D GO:0033280 IEP
Subcellular Localization
    axon GO:0030424 IDA
    intermediate filament GO:0005882 ISS
    peroxisome GO:0005777 ISO
    cytosol GO:0005829 ISO
    cytoskeleton GO:0005856 ISO
    cell leading edge GO:0031252 ISO
    type III intermediate filament GO:0045098 TAS
    plasma membrane GO:0005886 ISO
    neuron projection GO:0043005 ISO
    cytoplasm GO:0005737 ISS
    cell projection GO:0042995 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    nuclear matrix GO:0016363 IEA
    cell body GO:0044297 IDA
    extracellular exosome GO:0070062 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Vim in exosomes
1
Experiment ID 225
MISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|CD63
EV Enriched markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Vim
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DYNLL1 8655
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Vim is involved
No pathways found





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