Gene description for FGF16
Gene name fibroblast growth factor 16
Gene symbol FGF16
Other names/aliases FGF-16
MF4
Species Homo sapiens
 Database cross references - FGF16
ExoCarta ExoCarta_8823
Entrez Gene 8823
HGNC 3672
MIM 300827
UniProt O43320  
 FGF16 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for FGF16
Molecular Function
    fibroblast growth factor receptor binding GO:0005104 IEA
    growth factor activity GO:0008083 IEA
Biological Process
    Fc-epsilon receptor signaling pathway GO:0038095 TAS
    cell-cell signaling GO:0007267 TAS
    metabolic process GO:0008152 TAS
    neurotrophin TRK receptor signaling pathway GO:0048011 TAS
    regulation of sprouting angiogenesis GO:1903670 IDA
    regulation of endothelial cell proliferation GO:0001936 IDA
    organ morphogenesis GO:0009887 TAS
    epidermal growth factor receptor signaling pathway GO:0007173 TAS
    positive regulation of endothelial cell chemotaxis to fibroblast growth factor GO:2000546 IDA
    insulin receptor signaling pathway GO:0008286 TAS
    phosphatidylinositol-mediated signaling GO:0048015 TAS
    innate immune response GO:0045087 TAS
    positive regulation of brown fat cell proliferation GO:0070349 IEA
    signal transduction GO:0007165 TAS
    response to temperature stimulus GO:0009266 TAS
    fibroblast growth factor receptor signaling pathway GO:0008543 TAS
    regulation of MAP kinase activity GO:0043405 IDA
Subcellular Localization
    intracellular GO:0005622 TAS
    extracellular space GO:0005615 TAS
    extracellular region GO:0005576 TAS
 Experiment description of studies that identified FGF16 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for FGF16
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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