Gene description for COX19
Gene name COX19 cytochrome c oxidase assembly factor
Gene symbol COX19
Other names/aliases -
Species Homo sapiens
 Database cross references - COX19
ExoCarta ExoCarta_90639
Vesiclepedia VP_90639
Entrez Gene 90639
HGNC 28074
MIM 610429
UniProt Q49B96  
 COX19 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for COX19
Biological Process
    aerobic respiration GO:0009060 IBA
    mitochondrial respiratory chain complex IV assembly GO:0033617 IBA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    mitochondrial intermembrane space GO:0005758 IBA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified COX19 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for COX19
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COX19 is involved
No pathways found





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