Gene description for ZNF486
Gene name zinc finger protein 486
Gene symbol ZNF486
Other names/aliases KRBO2
Species Homo sapiens
 Database cross references - ZNF486
ExoCarta ExoCarta_90649
Entrez Gene 90649
HGNC 20807
UniProt Q96H40  
 ZNF486 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ZNF486
Molecular Function
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified ZNF486 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ZNF486
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZNF486 is involved
PathwayEvidenceSource
Generic Transcription Pathway TAS Reactome





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