Gene description for ADAMTS3
Gene name	ADAM metallopeptidase with thrombospondin type 1 motif, 3
Gene symbol	ADAMTS3
Other names/aliases	ADAMTS-4
Species	Homo sapiens
Database cross references - ADAMTS3
ExoCarta	ExoCarta_9508
Vesiclepedia	VP_9508
Entrez Gene	9508
HGNC	219
MIM	605011
UniProt	O15072
ADAMTS3 identified in sEVs derived from the following tissue/cell type
Saliva	19199708

Gene ontology annotations for ADAMTS3

Molecular Function     endopeptidase activity GO:0004175 IDA     metalloendopeptidase activity GO:0004222 IBA     metalloendopeptidase activity GO:0004222 NAS     metalloendopeptidase activity GO:0004222 TAS     protein binding GO:0005515 IPI     heparin binding GO:0008201 IEA     zinc ion binding GO:0008270 NAS Biological Process     in utero embryonic development GO:0001701 IEA     proteolysis GO:0006508 IBA     vascular endothelial growth factor production GO:0010573 IDA     protein processing GO:0016485 IDA     extracellular matrix organization GO:0030198 IBA     collagen fibril organization GO:0030199 IC     collagen fibril organization GO:0030199 NAS     collagen fibril organization GO:0030199 TAS     collagen catabolic process GO:0030574 NAS     collagen biosynthetic process GO:0032964 IDA     supramolecular fiber organization GO:0097435 IC     positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IDA     extracellular matrix GO:0031012 IBA     extracellular matrix GO:0031012 NAS     collagen-containing extracellular matrix GO:0062023 TAS     extracellular exosome GO:0070062 HDA