Gene description for Eif3m
Gene name eukaryotic translation initiation factor 3, subunit M
Gene symbol Eif3m
Other names/aliases Ga17
Species Mus musculus
 Database cross references - Eif3m
ExoCarta ExoCarta_98221
Entrez Gene 98221
UniProt Q99JX4  
 Eif3m identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Eif3m
Molecular Function
    translation initiation factor activity GO:0003743 IEA
    translation initiation factor binding GO:0031369 IDA
Biological Process
    translational initiation GO:0006413 IEA
    translation GO:0006412 IMP
    cytoplasmic translational initiation GO:0002183 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    eukaryotic translation initiation factor 3 complex GO:0005852 ISO
    eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541 IDA
 Experiment description of studies that identified Eif3m in exosomes
Experiment ID 263
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Eif3m
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eif3m is involved
No pathways found

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