Gene description for Cox5b
Gene name cytochrome c oxidase subunit Vb
Gene symbol Cox5b
Other names/aliases -
Species Mus musculus
 Database cross references - Cox5b
ExoCarta ExoCarta_12859
Vesiclepedia VP_12859
Entrez Gene 12859
 Cox5b identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cox5b
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    mitochondrial electron transport, cytochrome c to oxygen GO:0006123 IBA
    mitochondrial electron transport, cytochrome c to oxygen GO:0006123 IEA
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 HDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial membrane GO:0031966 ISO
    myelin sheath GO:0043209 HDA
    respiratory chain complex IV GO:0045277 IDA
    respiratory chain complex IV GO:0045277 ISO
 Experiment description of studies that identified Cox5b in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cox5b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cox4i1 12857
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
2 SNCA 6622
Affinity Capture-MS Homo sapiens
3 Cox5a  
Cross-Linking-MS (XL-MS) Mus musculus
4 Aco2 11429
Cross-Linking-MS (XL-MS) Mus musculus
5 Cox7a1  
Cross-Linking-MS (XL-MS) Mus musculus
6 Cox5b 12859
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
7 Mdh2 17448
Cross-Linking-MS (XL-MS) Mus musculus
8 Atp5o 28080
Cross-Linking-MS (XL-MS) Mus musculus
View the network image/svg+xml
 Pathways in which Cox5b is involved
No pathways found





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