Gene description for IL13
Gene name	interleukin 13
Gene symbol	IL13
Other names/aliases	IL-13 P600
Species	Homo sapiens
Database cross references - IL13
ExoCarta	ExoCarta_3596
Vesiclepedia	VP_3596
Entrez Gene	3596
HGNC	5973
MIM	147683
UniProt	P35225
IL13 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for IL13

Molecular Function     cytokine activity GO:0005125 IDA     interleukin-13 receptor binding GO:0005144 IEA     protein binding GO:0005515 IPI Biological Process     microglial cell activation GO:0001774 IEA     positive regulation of immunoglobulin production GO:0002639 IEA     inflammatory response GO:0006954 TAS     immune response GO:0006955 IEA     response to nematode GO:0009624 IEA     regulation of proton transport GO:0010155 IEA     response to selenium ion GO:0010269 IEA     positive regulation of gene expression GO:0010628 ISS     positive regulation of B cell proliferation GO:0030890 IEA     response to lipopolysaccharide GO:0032496 IEA     positive regulation of connective tissue growth factor production GO:0032723 IEA     positive regulation of interleukin-10 production GO:0032733 IGI     response to nicotine GO:0035094 IEA     interleukin-13-mediated signaling pathway GO:0035772 IDA     macrophage activation GO:0042116 IGI     positive regulation of macrophage activation GO:0043032 IEA     positive regulation of mast cell degranulation GO:0043306 IEA     response to ethanol GO:0045471 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     positive regulation of smooth muscle cell proliferation GO:0048661 IEA     positive regulation of protein secretion GO:0050714 IEA     negative regulation of inflammatory response GO:0050728 IGI     positive regulation of release of sequestered calcium ion into cytosol GO:0051281 IEA     cellular response to mechanical stimulus GO:0071260 IEA     negative regulation of transforming growth factor beta production GO:0071635 IEA     positive regulation of cold-induced thermogenesis GO:0120162 ISS     negative regulation of lung ciliated cell differentiation GO:1901247 NAS     positive regulation of lung goblet cell differentiation GO:1901251 NAS     negative regulation of complement-dependent cytotoxicity GO:1903660 IMP     positive regulation of pancreatic stellate cell proliferation GO:2000231 IEA     negative regulation of endothelial cell apoptotic process GO:2000352 IMP Subcellular Localization     extracellular region GO:0005576 IDA     extracellular region GO:0005576 TAS     extracellular space GO:0005615 ISS     cytoplasm GO:0005737 IEA     external side of plasma membrane GO:0009897 IEA