Gene description for FIBP
Gene name fibroblast growth factor (acidic) intracellular binding protein
Gene symbol FIBP
Other names/aliases FGFIBP
FIBP-1
Species Homo sapiens
 Database cross references - FIBP
ExoCarta ExoCarta_9158
Vesiclepedia VP_9158
Entrez Gene 9158
HGNC 3705
MIM 608296
UniProt O43427  
 FIBP identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for FIBP
Molecular Function
    fibroblast growth factor binding GO:0017134 IBA
    fibroblast growth factor binding GO:0017134 IPI
Biological Process
    fibroblast growth factor receptor signaling pathway GO:0008543 TAS
    platelet aggregation GO:0070527 HMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    mitochondrion GO:0005739 TAS
    endomembrane system GO:0012505 IEA
    membrane GO:0016020 IDA
    nuclear speck GO:0016607 IDA
 Experiment description of studies that identified FIBP in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for FIBP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GOLGA4  
Affinity Capture-MS Homo sapiens
2 VSNL1 7447
Affinity Capture-MS Homo sapiens
3 FASN 2194
Negative Genetic Homo sapiens
4 WDFY2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 GSK3B 2932
Two-hybrid Homo sapiens
6 CABLES2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 EIF6 3692
Affinity Capture-MS Homo sapiens
8 SAR1B 51128
Affinity Capture-MS Homo sapiens
9 ADSL 158
Affinity Capture-MS Homo sapiens
10 AP4B1  
Affinity Capture-MS Homo sapiens
11 CLEC2L  
Affinity Capture-MS Homo sapiens
12 CD6 923
Affinity Capture-MS Homo sapiens
13 EFNB1 1947
Affinity Capture-MS Homo sapiens
14 BRD2  
Affinity Capture-MS Homo sapiens
15 SLC5A6 8884
Affinity Capture-MS Homo sapiens
16 DLK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 GEMIN4 50628
Affinity Capture-MS Homo sapiens
18 AVPR1B  
Affinity Capture-MS Homo sapiens
19 APP 351
Reconstituted Complex Homo sapiens
20 PCNA 5111
Affinity Capture-MS Homo sapiens
21 IL13 3596
Affinity Capture-MS Homo sapiens
22 MIF 4282
Affinity Capture-MS Homo sapiens
23 KCNE3  
Affinity Capture-MS Homo sapiens
24 DNM1L 10059
Affinity Capture-MS Homo sapiens
25 CDK5 1020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 LDLR 3949
Negative Genetic Homo sapiens
27 OGT 8473
Affinity Capture-MS Homo sapiens
28 ZCCHC10  
Affinity Capture-MS Homo sapiens
29 CABLES1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 DLL1  
Affinity Capture-MS Homo sapiens
31 C2CD5 9847
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ZUFSP 221302
Affinity Capture-MS Homo sapiens
33 GRAMD1C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 SYT2  
Affinity Capture-MS Homo sapiens
35 KIAA0195 9772
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 RPA3 6119
Proximity Label-MS Homo sapiens
37 BRD3 8019
Affinity Capture-MS Homo sapiens
38 GBAP1  
Affinity Capture-MS Homo sapiens
39 FGF1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
40 BRD4 23476
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FIBP is involved
No pathways found





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