Gene description for SNAP25
Gene name	synaptosomal-associated protein, 25kDa
Gene symbol	SNAP25
Other names/aliases	CMS18 RIC-4 RIC4 SEC9 SNAP SNAP-25 bA416N4.2 dJ1068F16.2
Species	Homo sapiens
Database cross references - SNAP25
ExoCarta	ExoCarta_6616
Vesiclepedia	VP_6616
Entrez Gene	6616
HGNC	11132
MIM	600322
UniProt	P60880
SNAP25 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for SNAP25

Molecular Function     voltage-gated potassium channel activity GO:0005249 IEA     SNAP receptor activity GO:0005484 IBA     protein binding GO:0005515 IPI     lipid binding GO:0008289 EXP     myosin binding GO:0017022 IEA     syntaxin-1 binding GO:0017075 IBA     syntaxin-1 binding GO:0017075 IPI     protein domain specific binding GO:0019904 IEA     transmembrane transporter binding GO:0044325 IEA     calcium-dependent protein binding GO:0048306 ISS Biological Process     neurotransmitter uptake GO:0001504 NAS     exocytosis GO:0006887 IBA     chemical synaptic transmission GO:0007268 NAS     axonogenesis GO:0007409 IEA     long-term memory GO:0007616 IEA     locomotory behavior GO:0007626 IEA     associative learning GO:0008306 IEA     regulation of neuron projection development GO:0010975 IEA     synaptic vesicle exocytosis GO:0016079 TAS     synaptic vesicle docking GO:0016081 NAS     synaptic vesicle priming GO:0016082 IBA     endosomal transport GO:0016197 IEA     synaptic vesicle fusion to presynaptic active zone membrane GO:0031629 IBA     positive regulation of insulin secretion GO:0032024 IEA     SNARE complex assembly GO:0035493 IEA     regulation of insulin secretion GO:0050796 TAS     regulation of synapse assembly GO:0051963 IEA     long-term synaptic potentiation GO:0060291 IEA     potassium ion transmembrane transport GO:0071805 IEA     presynaptic dense core vesicle exocytosis GO:0099525 IEA Subcellular Localization     photoreceptor inner segment GO:0001917 IEA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISS     endosome GO:0005768 IEA     trans-Golgi network GO:0005802 IEA     cytosol GO:0005829 TAS     cytoskeleton GO:0005856 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 TAS     cell cortex GO:0005938 IEA     synaptic vesicle GO:0008021 IEA     voltage-gated potassium channel complex GO:0008076 ISS     actin cytoskeleton GO:0015629 IEA     membrane GO:0016020 ISS     lamellipodium GO:0030027 IEA     filopodium GO:0030175 IEA     growth cone GO:0030426 ISS     BLOC-1 complex GO:0031083 IDA     SNARE complex GO:0031201 IDA     SNARE complex GO:0031201 ISS     SNARE complex GO:0031201 TAS     vesicle GO:0031982 IDA     specific granule membrane GO:0035579 TAS     presynaptic membrane GO:0042734 TAS     neuron projection GO:0043005 ISS     neuronal cell body GO:0043025 IEA     axonal growth cone GO:0044295 IEA     perinuclear region of cytoplasm GO:0048471 IEA     synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex GO:0070032 IBA     synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex GO:0070033 IEA     synaptobrevin 2-SNAP-25-syntaxin-1a complex GO:0070044 IEA     tertiary granule membrane GO:0070821 TAS     ribbon synapse GO:0097470 IEA     extrinsic component of presynaptic membrane GO:0098888 IEA     glutamatergic synapse GO:0098978 IEA